| «2021-19» | São Paulo Grand Prix - I Grande Premio de São Paulo |
| 2021-11-14 | Interlagos - Autodromo José Carlos Pace - 71 laps × 4.309 km : 305.879 km (offset -60 m) |
| Pos | Grid | Car | Driver | Constructor | Laps | Time / Gap | Interval | Points |
|---|---|---|---|---|---|---|---|---|
| 1 | 10 | 44 | Lewis Hamilton | Mercedes | 71 | 1:32:22.851 | 198.664 km/h | 25 |
| 2 | 2 | 33 | Max Verstappen | Red Bull • Honda | 71 | +10.496 | +10.496 | 18 |
| 3 | 1 | 77 | Valtteri Bottas | Mercedes | 71 | +13.576 | +03.080 | 15 |
| 4 | 4 | 11 | Sergio Perez | Red Bull • Honda | 71 | +39.940 | +26.364 | 13 |
| 5 | 6 | 16 | Charles Leclerc | Ferrari | 71 | +49.517 | +09.577 | 10 |
| 6 | 3 | 55 | Carlos Sainz | Ferrari | 71 | +51.820 | +02.303 | 8 |
| 7 | 7 | 10 | Pierre Gasly | AlphaTauri • Honda | 70 | +1 lap | 6 | |
| 8 | 8 | 31 | Esteban Ocon | Alpine • Renault | 70 | +1 lap | 4 | |
| 9 | 12 | 14 | Fernando Alonso | Alpine • Renault | 70 | +1 lap | 2 | |
| 10 | 5 | 4 | Lando Norris | McLaren • Mercedes | 70 | +1 lap | 1 | |
| 11 | 9 | 5 | Sebastian Vettel | Aston Martin • Mercedes | 70 | +1 lap | ||
| 12 | 20 | 7 | Kimi Raikkonen | Alfa Romeo • Ferrari | 70 | +1 lap | ||
| 13 | 17 | 63 | George Russell | Williams • Mercedes | 70 | +1 lap | ||
| 14 | 13 | 99 | Antonio Giovinazzi | Alfa Romeo • Ferrari | 70 | +1 lap | ||
| 15 | 15 | 22 | Yuki Tsunoda | AlphaTauri • Honda | 70 | +1 lap | ||
| 16 | 16 | 6 | Nicholas Latifi | Williams • Mercedes | 70 | +1 lap | ||
| 17 | 19 | 9 | Nikita Mazepin | Haas • Ferrari | 69 | +2 laps | ||
| 18 | 18 | 47 | Mick Schumacher | Haas • Ferrari | 69 | +2 laps | ||
| 11 | 3 | Daniel Ricciardo | McLaren • Mercedes | 49 | engine | |||
| 14 | 18 | Lance Stroll | Aston Martin • Mercedes | 47 | undertray |
Fastest lap - 01:11.010 - 218.454 km/h - Sergio Perez (lap 71)